The hotel is found in the center of town near Plaza Mayor, the main square. The guests of the Gran Hotel Salamanca will discover many historical attractions in the area, including the Roman bridge and the New and Old Cathedrals. They will also find shops where they can pick up souvenirs and cafés where they can grab a bite to eat. The central location of the Gran Hotel Salamanca makes it easy for guests to walk to many of the popular tourist destinations in the area. To reach areas that are farther away, guests will be able to use rental cars or the plentiful public transportation.

All of the rooms at the Gran Hotel Salamanca are spacious and have air conditioning. The rooms also have alarm clock radios, TV, mini bars, bathrooms, and phones. In addition, the rooms have balconies.

Those traveling on business will be able to use the conference room at the hotel. The Gran Hotel Salamanca also offers an onsite bar where guests can have a drink and an onsite restaurant where they can dine on a variety of cuisine.